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Cancer cell senescence induced by anticancer treatments contributes significantly to cancer recurrence by enhancing cancer invasiveness and stemness 14,27

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Paulus WJ, Tschpe C (2013) A novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation

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This depth of human trial evidence provides greater confidence in safety characterization compared to peptides with primarily theoretical or animal-based safety data